Ohio & Tennessee River Cruises

Ohio & Tennessee River Cruises

In the wake of wayfarers, meet adventure.


In America’s heartland, nature unfolds the beauty of each season as we peacefully drift past rolling meadows, charming farms, rustic railroad bridges and towering bluffs. Friendly locals on shore greet our elegant craft like cherished friends as we cruise by. Coursing nearly 1,000 miles, the Ohio River forged through the surrounding valley and opened the West to early explorers and pioneers. Feel the same sense of wonder and possibility that fueled their courageous journeys.

Search Results:

(54) Ohio & Tennessee River Cruises Available

Results per page
Sort by: Sailing Date | Voyage Title | Price (Low to High)
American Duchess
Apr 05 - Apr 13

Memphis to Clarksville (Nashville)

Civil War

Civil War The rivers of the South were of great strategic value as both a transportation and communication route during the Civil War. Experience authentic Southern culture as you journey through living history and explore the legacy of the Civil... Learn More

Duration
9 Days
Fares from
$2,399
American Duchess
Apr 12 - Apr 20

Clarksville (Nashville) to St. Louis

Music of America

MUSIC OF AMERICA - A very special guest will bless these cruises. Country music icon and writer of “God Bless the USA,” Lee Greenwood, is as American as apple pie – and American Queen Steamboat Company, for... Learn More

Duration
9 Days
Fares from
$2,399
American Duchess
Apr 19 - Apr 27

St. Louis to Cincinnati

American Culinary Experience

Sample the tantalizing array of sights, sounds and flavorful cuisines unique to various river regions while discovering the historic significance and quaint charms of small-town America on our American Culinary Experience cruise. This specially... Learn More

Duration
9 Days
Fares from
$2,299
American Duchess
Apr 26 - May 04

Cincinnati to Louisville

Kentucky Derby Cruise

KENTUCKY DERBY CRUISE: The first weekend of May is an exciting time to celebrate the honored tradition of the Kentucky Derby.® This thoroughbred race has taken place under the iconic Twin Spires of Churchill Downs every year since... Learn More

Duration
9 Days
Fares from
$2,999
American Duchess
May 03 - May 11

Louisville to Clarksville (Nashville)

American Music Festival

AMERICAN MUSIC FESTIVAL - A very special guest will bless this voyage. Country music icon and writer of “God Bless the USA,” Lee Greenwood, is as American as apple pie – and American Queen Steamboat Company, for that matter.... Learn More

Duration
9 Days
Fares from
$2,999
American Duchess
May 10 - May 18

Clarksville (Nashville) to Memphis

American Music Festival

AMERICAN MUSIC FESTIVAL - A very special guest will bless this voyage. Country music icon and writer of “God Bless the USA,” Lee Greenwood, is as American as apple pie – and American Queen Steamboat Company, for that matter.... Learn More

Duration
9 Days
Fares from
$2,699
American Countess
May 31 - Jun 07

Alton (St. Louis) to Louisville

Chairman's Cruise

CHAIRMAN'S CRUISE - Have you ever wondered what it would be like to spend a week with a company Chairman and his wife?  If you so, then this cruise is for you.  Join American Queen Steamboat Company Chairman, John Waggoner, and... Learn More

Duration
8 Days
Fares from
$2,099
American Countess
Jun 07 - Jun 14

Louisville to Pittsburgh

Maiden Voyage to Pittsburgh

Uncover America's bucolic heartland as you travel the tranquil waters of the Ohio River from Louisville to Pittsburgh, the iconic city where names like Carnegie and Bessemer created the steel-making capital of the world. Themes: •... Learn More

Duration
8 Days
Fares from
$2,299
American Countess
Jun 14 - Jun 21

Pittsburgh to Louisville

Ohio River Sojourn

The upper reaches of the Ohio River are painted with pictureque hills, renowned cities and quaint river towns that welcome each visitor with open arms. These thoughtfully designed itineraries are some of the most sought after voyages for our... Learn More

Duration
8 Days
Fares from
$2,299
American Countess
Jun 21 - Jun 28

Louisville to Pittsburgh

Ohio River Sojourn

Uncover America's bucolic heartland as you travel the tranquil waters of the Ohio River from Louisville to Pittsburgh, the iconic city where names like Carnegie and Bessemer created the steel-making capital of the world. Themes: •... Learn More

Duration
8 Days
Fares from
$2,299
Results per page